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DETERMINATION OF IN-HOSPITAL CONSEQUENCE OF AKI WITH ETIOLOGY AMONG NEW BIRTHS

Dr. Awais Akram, Dr Maryam Mehmood, Dr Jaweria Sana

Objective: This research work aimed to find out the correlation in-hospital consequence of acute kidney injury (AKI) with etiology in new births at our institute. Methodology: This was a descriptive transverse research work conducted at Pediatric Department of Sir Ganga Ram hospital, Lahore with the use of the non-probability technique of sampling From July 2018 to July 2019. Total one hundred and one new births diagnosed with AKI were the part of this research work. We assessed the etiological factors and we followed these patients till their discharge to screen the in-hospital results. Result: Out of total one hundred and one newborns, 74.30% (n: 75) were male babies whereas 25.70% (n: 26) were baby girls. The average age of these patients was 7.590 ± 6.130 days with a range of age from one to twenty eight days. The average age of the males was 5.730 ± 7.20 days whereas the average age of the girls was 6.770 ± 6.160 days. The average weight of the new births was 2545.050 ± 600.420 grams with a range of weight from 1000 to 4000 grams. The average level of serum potassium was 4.940 ± 0.920 mgEq/L with a range from 3.10 mgEq/L to 7 mgEq/L. The average level of urea 73.350 ± 27.650 mg/dl with a range from 18.0 mg/dl to 206.0 mg/dl. The average level of serum creatinine was 1.980 ± 0.270 mg/dl with a range from 1.60 mg/dl to 2.80 mg/dl. The average level of serum sodium was 145.720 ± 12.640 mgEq/L with a range from 126.0 to 166.0 mEq/L. Total 80.20% (n: 81) babies were term babies whereas 19.80% (n: 20) babied were pre-term. Among total studied population, 28.70% (n: 29) delivered through vagina whereas 71.30% (n: 72) delivered through CS (Cesarean Section). We noted the delayed crying in 47.50% (n: 48), dehydration in 12.90% (n: 13), sepsis in 35.60% (n: 36) & renal malformation in 4.0% patients. The rate of mortality in these patients was 14.90% (n: 15) whereas 85.10% (n: 86) infants got discharge from department after complete recovery. Conclusion: Asphyxia & sepsis are the most important etiological factors responsible for the AKI in new births which have strong association with the high rate of morbidity as well as mortality. This complication is more frequent in males as compared to females. The rate of mortality was much high in our patients and it has strong association with the female gender. There was a strong association of the mortality with the increased level of serum urea & sodium. Keywords: AKI, association, mortality, sodium, recovery, morbidity, urea, methodology.

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