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TITLE:

DEXMEDETOMIDINE IMPROVES EFFECTIVENESS OF 0.27% ROPIVACAINE FOR POSTOPERATIVELY ANALGESIA IN PEDIATRIC CAUDAL EPIDURALS

AUTHORS:

Dr. Maryam Yaqoob, Dr Sadia Riaz, Dr Fatima Kazim

ABSTRACT:

Background & Objectives: Caudal epidural block remains the maximum innocent, dependable also actual procedure in pediatric cases nevertheless solitary shot caudal epidural block was short period of analgesia that may remain lengthy through adding of adjuvants comparable opioids, clonidine, ketamine orα 2 agonists laterally by resident anesthetic agents. Our current forthcoming randomized research remained led to measure effectiveness of adding of dexmedetomidine to caudal 0.26% ropivacaine for postoperatively analgesia. Methodology: This current research conducted in Lahore General Hospital Lahore from April 2018 to March 2019. Seventy ASA physical position 1 and 2 Pediatric respondents aged 7 months to 7 years remained randomly owed into 2 sets by 35 cases in every set: Group R (n = 35) established caudal 0.26% ropivacaine 2 ml/ kg also normal saline (0.6 ml) whereas Set RD established caudal 0.26% ropivacaine 1 ml/kg + dexmedetomidine 2 μg/kg (0.6 ml). Postoperatively discomfort, period of analgesia, release analgesic condition, postoperatively sedation scores, also hemodynamic variations laterally by problems remained noted. Results: The period of analgesia remained pointedly lengthier in Set RD (798.01 ± 58.22 minutes) associated to Set R (364.32 ± 34.46 minutes), (p < 0.0002). The over-all quantity of measures of release analgesic needed remained minor in Set RD in assessment to Set R. The respondents in Set RD accomplished developed sedation scores as compared to Set R, that remained extremely substantial (p < 0.0002). In opposing belongings, occurrence of postoperatively agitation (7.67%), also PONV (4.36%) remained understood solitary in Set R once associated to Set RD. Conclusion: Dexmedetomidine may remain exercised as the adjuvant to solitary shot caudal epidural by means of 0.26% ropivacaine for real postoperatively analgesia in pediatric cases as this is suggestively protracted period of analgesia laterally through condensed rescue analgesic needed also negligible side effects. Keywords: Ropivacaine; Caudal epidural; Postoperatively analgesia; Pediatric; Rescue analgesic.

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