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TITLE:

ANALYSIS OF REFERENCE RANGE OF SIGNS AND SYMPTOMS OF HYPOTHYROIDISM IN POPULATION OF LAHORE

AUTHORS:

Dr. Wasif Altaf, Dr. Muhammad Awais, Dr. Muhammad Abdullah,

ABSTRACT:

Background: This study was designed for the evaluation of the difference in the common signs and symptoms of hypothyroidism in our population from already available literature. Methods: In this study we have compared the symptoms and signs of hypothyroid and euthyroid patients visiting to Services Hospital from April 2017 to October 2017. We compared the 18 common signs and symptoms of hypothyroidism in our patients and analyzed by SPSS software. Results: Of the 2483 patients visiting to the HOSPITAL , 665 patients were included in the study and were examined. After the laboratory investigations, 98 were identified as the cases of hypothyroidism, the rest were declared as euthyroid and selected as controls. Lethargy, cold intolerance, constipation and paresthesia were the commonest symptom while facial oedema and bradycardia were the most prevalent sign in our population. Conclusions: The most common signs and symptoms of hypothyroidism in Pakistan (that is one of the iodine deficient areas in Pakistan) were different from other studies. It seems that strong clinical suspicion on the basis of symptoms and signs elicited by physicians and laboratory confirmation are the only reliable methods for diagnosis of hypothyroidism. significantly among different populations owing to their climate, education status and awareness about the disease.

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