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TITLE:

ANALYSIS OF DIFFERENT BLOOD BIOMARKERS OF ALLERGY DURING PREGNANCY IN PAKISTAN

AUTHORS:

Laraib Hafeez, Quratulain Khalil, Hafiza Fatima Naseem

ABSTRACT:

Objectives: The basic aim of the study is to analyze the different blood biomarkers of allergy during pregnancy in Pakistan. Methodology of the study: This cross sectional study was conducted at RHC Hajipur during January 2019 to July 2019. This study was conducted to analyze the different blood biomarkers of allergy during pregnancy. For this purpose we select the 100 pregnant women which was at different stages of pregnancy. Then we collect the blood samples of each women for further biochemical analysis and antioxidants analysis.Result: Serum allergy biomarkers shows that in pregnancy women become more sensitive to allergy as compared to normal condition. The levels of inflammatory biomarkers in blood is at increased level as compared to normal women. The levels of IL-6 and IL-8 was significantly higher in pregnant women.Conclusion: We report a positive, statistically significant association between maternal allergy biomarkers exposure and elevated cord blood concentrations of the epithelial cell derived cytokines TSLP and IL-6 and 8. Our results indicate that both GWG and diet are related to inflammatory status of pregnant women.

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