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ANALYSIS OF RECENT ADVANCES AND TREATMENTS OF NEPHROTIC SYNDROME

Adil Ahmed, Muhammad Mustafa, Uzair Ahmad

Objectives of the study: The main objectives of the study is to find the recent advances and treatments of nephrotic syndrome in Pakistan.Methodology of the study: This cross sectional study was done at Jinnah Hospital Lahore during 2018 to 2019. This study was done according to the rules and regulations of hospital ethical authority. The data was collected from 100 patients of both genders which was suffering from nephrotic syndrome. The basic purpose of this data is to find and investigate the recent advances and treatments of nephrotic syndrome in Pakistani hospitals.Results: The study group comprised of 100 patients 72 (93.5%) were initial steroid resistant and 28 were late non-responders. Gender distribution showed 49 (63.6%) males and 28 (36.4%) females with a ratio of 1.75. Age range of patients was 1-15 years with a mean of 8.11 +3.58 years. Sixty nine (89.6%) patients underwent renal biopsy. Patients with focal segmental glomerulosclerosis (FSGS) were least likely to respond to treatment followed by mesangio proliferative glomerulonephritis and minimal change disease.Conclusion: Nephrotic syndrome can increase your child’s risk of infection and blood clots. It always affects both kidneys and usually appears in the early years of your child’s life. Most children with this disorder outgrow it by young adulthood. We conclude that NS in children is a difficult disease with significant morbidity.

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