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A CROSS-SECTIONAL STUDY TO DETERMINE THE OCCURRENCE OF DIABETES MELLITUS IN NON-ST ELEVATION MYOCARDIAL INFARCTION (NSTEMI) PATIENTS

Dr Atiqa Usman, Dr Nayab Zahra, Dr Sadia Saleem

Objective: To determine the occurrence of diabetes mellitus in non-ST segment elevation myocardial infarction. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out at Services Hospital, Lahore from August,2018 to July, 2019. Material and Methods: In this study three hundred fifty-two (352) patients with non-ST elevation myocardial infarction (NSTEMI) who fulfilled the inclusion criteria were studied while they were admitted to the hospital. They were divided into diabetic and non-diabetic groups. Frequency of age, gender, rising levels of cardiac biochemical markers, plasma glucose and HbA1c were seen in both diabetic and non-diabetic patients. Results were obtained by using chi -square method and independent T-test. Results: Out of 352 patients of NSTEMI 193 were diabetics. The study population was categorized in three groups according to age as; 30-45, 46-60, and 61-75 years respectively. It was found that 46 -60 years group was most frequently affected with frequency of 46.1%, p<0.001 with male predominance as 67.9% and females as 32.1%. Cardiac biochemical markers were raised with mean for CK 528.51 U/ L SD ± 275.82 and CK MB 79.39 U/ L SD ± 32.5, p<0.001 respectively. Raised fasting plasma glucose was found in 189 patients mean 8.74 mmol/ L SD ± 1.52, p<0.001 and elevated HbA1c seen in 187 patients mean 7.94 % SD ± 0.83, p<0.001. Conclusion: Despite modern therapies for unstable angina (UA) / NSTEMI diabetes is an independent cardiovascular risk factor, therefore, we need aggressive strategies to manage the high-risk group of patients. Keywords: Diabetes mellitus, Frequency, Non-ST segment elevation myocardial infarction.

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