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TITLE:

A STUDY ON EPIDEMIOLOGY OF KIDNEY DISEASE IN A PAKISTANI POPULATION

AUTHORS:

Fatima Zafar, Muhammad Noman Shakir, Zunera Javed

ABSTRACT:

Introduction: Chronic Kidney Disease (CKD) is progressive loss of renal function. CKD is a great burden on Pakistan's healthcare resources. Lack of screening and risk identification often result in delayed treatment and implementation of preventive measures. Aim and objectives: The basic aim of the study is to analyze epidemiology of chronic kidney disease in a Pakistani population. Methodology of the study: This cross sectional study was conducted in Bahawalpur Victoria Hospital, Bahawalpur during March 2019 to August 2019. This study was basically conducted for the analysis of role of RAAS in the management of CKD. A diagnosis of chronic tubulo-interstitial disease was made based on history of polyuria, nocturia with low-specific gravity of urine and low or normal blood pressure associated with small kidneys on ultrasound. Results: A total of 50 patients were initially included in the study, with a male to female ratio of 1:1. A total of 50 patients were considered for final analysis based on data adequacy. The mean age of the population was 46.3 years, with the minimum age being 20 years and the maximum being 83 years. Common causes of CKD identified in these patients included diabetic nephropathy, glomerulonephritis, hypertension, tubulo-interstitial disease and renal stone disease. Conclusion: It is concluded that considering the alarmingly high prevalence of CKD compared to other countries and its impact on morbidity, mortality and financial burden, we recommend that early detection and treatment of the disease should be the priority in healthcare policies of the region

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