::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO KNOW THE INCIDENCE OF LEUCOCYTOSIS IN ACUTE ISCHEMIC STROKE AND ITS EFFECT ON SHORT TERM MORBIDITY

AUTHORS:

Dr Rabia Nasir Kakar, Dr Kaynat Fatima, Dr Sara Mandokhail

ABSTRACT:

ackground:Strokeisamajorhealthproblemworldwidebecauseofitshighrisksofmorbidityandmortality.Approximately15millionpeopleworldwidesufferfromstrokeannuallyofwhich5.5milliondiewhiletheremainingareleftwithpermanentdisabilityandover50%ofcasesoccurinAsians.Aimofthestudywastofindouttheincidenceofleucocytosisinacuteischemicstrokeanditseffectonshorttermmorbidity.StudyDesign:DescriptiveCross-Sectionalstudy.PlaceandDurationofStudy:ThisstudywasconductedattheDepartmentofNeurology,CivilHospitalQuettaforsixmonthsJanuary,2020toJuly,2020.MaterialsandMethods:Datawascollectedbynon-probabilityconsecutivesamplingtechnique.126adultpatientswithischemicstrokewereincludedinthestudy.Fullbloodcountwasobtainedforallpatientsonadmissionandpossibilityofinfectionruledoutwithhistoryandrelevantclinicalexamination.PresenceofdisabilitywasassessedusingModifiedRankinScale(mRS).Results:Atotalnumberof126patientshavingischemicstrokewereincludedinthisstudy.Themeanagewas61.9years.114(64.4%)weremales.Leukocytosiswasseenin61(76.25%)ofthepatientswithsignificantmorbidity,whereas19(23.75%)ofpatientswithmorbidityhadnoleukocytosis.Inpatientswithoutanysignificantmorbidityleukocytosiswasseeninonly12(26.09%)ofthepatients.Conclusion:Itisconcludedfromthisstudythatearlyleukocytosisinischemicstrokepatientsisassociatedwithincreasemorbidityandcanthereforebeconsideredasaprognosticfactor.KeyWords:Leukocytosis,IschemicStroke,Morbidity