::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO DETERMINE THE SERO-PREVALENCE OF HEPATITIS B AND C AMONG BLOOD DONORS VISITING MAYO HOSPITAL, LAHORE

AUTHORS:

Dr Muhammad Abubakar, Dr Zara Munawar, Dr Muhammad Ali

ABSTRACT:

Objective: Hepatitis B and Hepatitis C are considered to be a worldwide health issue especially in developing countries like Pakistan. Most of infectious diseases are spread through blood transfusion. In Pakistan, the social norms, cultral diversity, poor health delivery system, lack of proper health facilities and unsafe blood transfusion ways are responsible for high prevalence of Hepatitis B and C from blood donors to the recipients. Aim of the study was to determine Sero-prevalence of Hepatitis B and C virus among blood donors in local population. Study Design: Descriptive, retrospective, cross-sectional Study Place and Duration of Study: This study was conducted at the Blood Bank of Mayo Hospital, Lahore from August 2019 to February 2020. Materials and Methods: Data from August 2014 to July 2019 was included. Blood grouping was done and serum extracted from blood donors was screened by the use of Immuno-Chromatographic Diagnostic Kits (ICT) for Hepatitis B(HBsAg) and Hepatitis C (Anti-HCV). Results: A total number of 39114 subjects were investigated for Hepatitis B and C viral infections. Out of these 1775 (4.54%) were found to be Anti-HCV positive, 467 (1.19%) were HBsAg positive and 30 (0.08%) were positive for both. Hepatitis B infection was found more prevalent (33.83%) in blood group B and the highest prevalence of Hepatitis C was found in blood group O. Conclusion: Prevalence of Hepatitis C is found high among blood donors visiting DHQ Teaching Hospital Sahiwal, which warrants mandatory regular screening for all blood donations to prevent transfusion related transmission of infections. There is dire need of implementation of community based preventive measures and improved strategies to decrease Sero-prevalence across the region. Key Words: Anti-HCV, Hepatitis B, Hepatitis C, HBsA, Immuno-Chromatographic Diagnostic Kits (ICT).