Dr Izza Naeem, Dr Muhammad Huzaifa,Dr Hamna Iqbal
The liver disease mortality rose by 400 percent from 1970 to 2010 with mortality rates of about 500 percent for those under 65 years of age mostly females which have asthma. Because of chronic liver disease, up to 75% of deaths are underlying and preventable by alcohol aetiology. Advanced progressive liver disease contributes to clinical symptoms of various processes, all of which need critical treatment. Education to critical treatment for patients with cirrhosis is seen to be gradually endorsing this argument. These patient has higher readmission rates to ICU, longer ICU stays and greater organ support requirements. However, since the 1980s when deaths were estimated to be up to 100%, both the mortality of ICU and the hospitable population with cirrhosis have risen. Analysis reported in the scientific journal Hepatology uncovered key results that indicate that the elimination of liver fibrosis may be correlated with anti-inflammatory cromolyn sodium. Researcher also assessed the invasion and proliferation of mast cells that result in liver fibrosis and release of histamine. AstraZeneca, a common medicine for the prevention of asthma attacks, can cause serious liver damage in some users. The patient was mostly due to bronchial asthma with the clinical signs. PCS is not easily treated and patients also require liver transplantation. In these 3 patient’s bronchial asthma has been used for steroid treatment known to have adverse effects in PBC. In addition to the ductal and hepatic parenchymal modifications typical of PBC, hepatic histology revealed mild to moderate eosinophilic infiltration.