- CODEN : IAJPBB
- issn 2349-7750
TITLE:
INFLUENCE OF FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) IN THE ANALYSIS OF MALIGNANT THYROID NODULES
AUTHORS:
Dr Moazzam Mumtaz Khan, Dr Qirat Nauman, Dr Nizam Uddin
ABSTRACT:
Aim: The aim of this study is to determine the importance of fine needle aspiration in the diagnosis of malignant thyroid nodules. Place and Duration: In the ENT and Surgical Unit-II of Nishtar Hospital Multan for one-year duration from August 2019 to August 2020. Material and methods: The trial consisted of 82 patients with a single thyroid nodule who met the inclusion criteria. Our study included 82 cases involving 57 women and 25 men, with a female to male ratio of 2.28: 1. The age of the patients ranged from 16 to 65 years, and the mean age was 42.56 + SD 11. 60 years. Most patients reported in the 3rd and 4th decades, and then in the 5th and 2nd decades. The diagnostic performance of fine needle aspiration cytology (FNAC) in this study was 82.92%, sensitivity 88.09%, specificity 77.50%, and positive predictive value 80.43%. After collecting a detailed history, thorough examination, appropriate examination and informed consent, fine-needle aspiration cytology was performed in all cases by the same cytopathologist. The thyroid gland was operated on and the samples were examined by the same histopathologist. Statistical analysis was performed using the Statistical Program for Social Sciences (SPSS version 11). Results: One hundred and twenty-six patients entered the study, of whom 77 (61%) were women and 49 (39%) were men. The mean age was 26.9 ± 7.7 years. As many as 79.4% of patients complained about cosmetic effects, 39.7% for respiratory problems and 4.8% for olfactory problems. The cause of the doctor's claim was significantly related to the age and sex of the patients, as well as the experience of surgeons. Conclusion: FNAC is a key principle in the diagnosis of a single thyroid nodule as it is a safe, minimally invasive and cost-effective diagnostic tool. Key words: cytology of fine-needle aspiration, histopathology, solitary thyroid nodule
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