::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

TO STUDY THE RISK FACTORS ASSOCIATED WITH GASTRO-ESOPHAGEAL REFLUX DISEASE

AUTHORS:

Dr Arooj Fatima Hashmi, Dr Hassan Rafaqat, Dr. Mohsin Riaz

ABSTRACT:

Objective: Gastro-esophageal reflux disease (GERD) is one of the commonly known disorders in upper gastrointestinal tract1. GERD has been observed in an increasing extent in Europe as well as United States of America. Aim of the study was to determine the risk factors associated with Gastro-esophageal reflux disease (GERD), in a tertiary care Hospital of Karachi. Study Design: Prospective, cross sectional study Place and Duration of Study: This study was conducted at the Department of Internal Medicine and Gastroenterology, Mayo Hospital Lahore from April 2019 to April 2020. Materials and Methods: Attendants of patients sitting in the waiting area with no comorbid, and who were non-smoker and non-alcoholic were recruited after taking informed consent. Data was entered in given performa. Logistic regression was applied with 95% confidence interval. Results: Total 2191 participants were included in our study. 1130 patients (51.6%) were males and 1061 (48.4%) were females, with mean age of 33.92+12.36 years. GERD symptoms were present in 760 patients (34.7%). GERD symptoms were common in patients taking spicy meals (37.2%) and in urdu speaking ethnic group (52.5%). In those who had a high waist hip ratio, 0.9 +-0.15 waist height ratio 0.52+-0.07 and waist circumference ratio 84.57+-10.92. Conclusion: Gastro-esophageal reflux disease is common in our population and there is significant inverse association of GERD with Waist hip ratio and waist height ratio. Keywords: Gastro-esophageal reflux disease, body mass index.