- CODEN : IAJPBB
- issn 2349-7750
TITLE:
RISK OF HEPATOMEGALY IN TYPHOID FEVER: A STUDY ON CURRENT CLINICAL ASPECTS
AUTHORS:
Dr Marium Riaz Nawab, Dr Safa Sajjd, Dr Hafsa Hashmi
ABSTRACT:
Objectives: To cha:racterize the clinical picture, biochemical features and prognosis in typhoid hepatitis. Material and methods: This prospective, randomized, controlled parallel study of 100 children up to 12 years of age admitted in Al Nafees Hospital, Islamabad for six months duration from March 2020 to August 2020 with clinical and / or laboratory diagnosis of typhoid fever admitted to a pediatric ward was analyzed in terms of demographic data such as age, gender, clinical features and laboratory test results. Results: 08 were under the age of one, and 34 were under the age of five. The dominant symptoms were liver enlargement, spleen enlargement, fever, abdominal pain, vomiting, and headache. Febrile seizures were the main symptom in 2 patients, all of whom were under the age of five. No intestinal perforation was found in any of the patients. Anemia was present in 61%, leukopenia in 31% and thrombocytopenia in 38%. Elevated levels of serum alanine and aspartate aminotransferase (50> / U / L) were observed in 28% of our patients. Conclusion: Research suggests that in the diagnosis of typhoid, hematological results and the level of transaminases related to hepatomegaly should be interviewed. Key words: typhus, transaminases, blood picture
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NLM ID:101711216 [Serial]
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