::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ANALYSIS OF ORAL ASSOCIATION OF SERUM ZINC LEVEL WITH FEBRILE SEIZURES IN CHILDREN

AUTHORS:

Dr. Muhammad Saeed, Dr. Nabeel Mushtaq Kiani, Dr. Mohammad Ali Shahid

ABSTRACT:

Introduction: Febrile seizures occur in young children at a time in their development when seizure threshold is low. They typically occur relatively early in an infectious illness usually during the rise of temperature curve. Aims and objectives: The basic aim of the study is to analyze the oral association of serum zinc level with febrile seizures in children of Pakistan. Material and methods: This study was conducted at Sughran Shafi Medical Complex Narowal during Jan 2019 to May 2019. The children of 1 year to 6 years were considered in this study. The patients who had any evidence of central nervous system infection, epilepsy, metabolic seizures or those who are already on zinc therapy for any other ailment like malnutrition, diarrhea, pneumonia or acrodermatitis enteropathica were excluded. Results: Frequency of low serum zinc level was 26% in children with febrile seizures. Sixty three (63%) children were between 6 months to 3 years of age while rest of the 37(37%) were between >3 years to 6 years of age. Upper respiratory tract infection was the most frequent cause of fever evident in 24 children (24%) followed by tonsillitis 17 (17%), pneumonia 16 (16%), urinary tract infection 16 (16%), otitis media 15 (15%), and bronchiolitis 12 (12%) in children having febrile seizures. Conclusion: It is concluded that low serum zinc levels are fairly sufficient to support the hypothesis that Zinc deficiency could be a potential risk factor for febrile seizure in children.