::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ASSESSMENT OF THE ASSOCIATION BETWEEN PR AND GASTRIC MALIGNANT EXPANSION AFTER THE DESTRUCTION OF H. PYLORI

AUTHORS:

Dr. Rafia Batool, Dr. Frasat Ullah, Dr. Faisal Mahmood Sadiq

ABSTRACT:

Aim: We recently detailed an inversion of the red and white tint of the gastric corpus in some patients after destruction, and referred to it as the "wonder of inversion on the marginal mucous membrane" (RP), which is regularly visible in patients who create gastric malignant growth after annihilation. In this way, we conducted a cross-sectional study to evaluate the relationship between PR and gastric malignant growth after the destruction of H. Pylori, and we analyzed PR histologically. The characteristic endoscopic highlights of the gastric mucosa, which are signs of malignant growth after the successful annihilation of H. Pylori, have not been fully explained. Materials and Methods: Patients with a history of successful annihilation who underwent esophago-gastro-duodenoscopy in our clinic between January 2018 and April 2019 were temporarily enrolled. Our present research was conducted at Sir Ganga Ram Hospital, Lahore. The quantities of tumour recently analyzed in positive and negative PR samples were evaluated. In addition, the red and white areas of RP-positive patients were examined by thin-band imaging with amplifying endoscopy, and histologically examined using examples of biopsies. Results: 30 (34.8%) indicated RP, out of 85 patients who were examined. Six malignant tumour were found in the RP-positive group and one in the RP-negative group (p<0.02). NBI-ME appeared as round pits without light blue peaks in white areas, and round pits with PLC-shaped structures or villus with PLC or dark white substance in red areas. All examples of white zone biopsies had background organs, and all those of red territories showed intestinal metaplasia. Conclusion: Patients with RA generally develop gastric disease after annihilation. Key words:H. Pylori, Narrow-band imaging, Eradication therapy, Gastric cancer, Magnify¬ing endoscopy.