::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

THE RELATIONSHIP OF SERUM AMINOTRANSFERASES WITH SODIUM AND CREATININE AND THEIR ASSOCIATION WITH INTERDIALYTIC WEIGHT GAIN (IDWG)

AUTHORS:

Dr. Tahira Tabassam, Dr. Muhammad Ramzan, Dr. Muhammad Salman, Azhar Hussain

ABSTRACT:

Introduction: More than 500,000 people in the United States live with end-stage renal disease (ESRD). The development of chronic kidney disease (CKD) and its progression to this terminal disease remains a significant source of reduced quality of life and significant premature mortality. Materials and Methodology: Patients of end stage renal disease with hepatitis C infection were identified among patients visiting the hemodialysis center of Lahore General hospital and Sheikh Zayed hospital, Lahore. They were only positive for HCC antibodies by detecting HCV RNA by PCR. The patients that were coinfected with HBV and HCV and negative for HCV and HbAsg were not included. Total 56 patients were engaged in this process. Results: We studied on 56 patients.Paired sample T-test analysis shows a statistically significant relationship between blood flow speed and IDDWG (P<0.01).37(66.1)had arthralgias,19(33.9) had no arthralgias.47(83.9)were fatigued and 9(16.1) had no fatigue.17(30.4) had drowsiness,39(69.6) had no drowsiness.48(85.7) had dry skin,8(14.3) had no dry skin.33(58.9)had itchy skin,23(41.1) had no itchy skin.19(39.9) were easily bruised,37(66.1) were not easily bruised.18(32.1)had nail changes,37(66.1) had no nail changes.37(66.1)had cramps,19(33.9)had no cramps.37(66.1)had backache,19(33.9)had no backache.21(37.5)had chestpain,35(62.5)had no chestpain.37(66.1)had irritability,19(33.9)had no irritability. Conclusion: This study augments the relationship of serum aminotransferases with sodium and creatinine and their association with IDWG. Keywords: Serum aminotransferases, sodium, creatinine, IDWG.