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TITLE:

A RESEARCH STUDY ON PACE OF HAPPENING OF DYSLIPIDEMIA IN PATIENTS OF LUPUS NEPHRITIS

AUTHORS:

Dr Hafiz Muhammad Usman Tariq, Dr M Waqas Saleem, Dr Asif Hassan

ABSTRACT:

Objective: The main objective of this study and assessment is to find out the rate of occurrence of dyslipidemia in the patients suffering from LN (Lupus Nephritis) and its relationship with the proteinuria’s degrees. Methodology: We noted the demographic variables and characteristics of their disease. This transverse research work included sixty five patients who completed the standard of American Collegeof Rheumatology (ACR) for SLE and present with renal involvement, appearing in Sir Ganga Ram Hospital, Lahore from September to December 2018. After complete twelve hours of overnightfasting, we evaluated their samples of blood from TC (Total Cholesterol), TG (Triglycerides), HDL (High Density Lipoprotein and LDL (Low Density Lipoprotein). We divided the patients into groups on the basis of proteinuria degree as having proteinuria greater than 1gm or equal or less than 1gm. We used the SPSS V.21 for analysis of data. We performed the correlation of the individual profiles of lipids with the proteinuria’s degree. Results: In Sir Ganga Ram Hospital, Lahore from September to December 2018, the most common abnormality of lipid discovered in this research work was hypertriglyceridemia (58.50%). TC &LDL-C was much high in 55.40% and 30.80% patients correspondingly. We found the low HDL in 21.50% patients. We also noticed the enhanced dyslipidemia’s frequency in those patients who were present with proteinuria of greater than 1gm (P<0.050). Conclusion: We examined the dyslipidemia with high pace of occurrence in the patients suffering from LN and it has strong association with the proteinuria’s degree. Keywords: ACR, HDL, TC, TG, LDL, Association, dyslipidemia, Lupus Nephritis, SLE, correlation, occurrence.

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