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TITLE:

TYPE II DIABETES MELLITUS PREVALENCE IN CHRONIC HEPATITIS C VIRUS INFECTED PATIENTS

AUTHORS:

Maryam Shabbir, Memoona Khalid, Hafiz Muhammad Umar Farooq

ABSTRACT:

Objective: The main objective of this research was to establish the prevalence of type II diabetes mellitus in hepatitis c virus infected patients. Place and duration of study: This research was performed from june 2019 to january 2020 for eight months in Nishtar Hospital Multan. Materials and Methods: 200 patients of 18 to 60 years of age in total were chosen for this review. This research included both men and women with a positive hepatitis c virus infection and having no previous or insignificant history of DM (diabetes mellitus). For HCV identification, a qualitative PCR test was performed. Patients were labelled as diabetics having fasting level blood glucose higher than 126 mg/dl. For collecting the details, a proforma of pre-designed was used. All the patients were given informed consent. The approval of the Ethical Committee was adopted. Using the 20th version of SPSS, data were analysed. Results: In this study, 200 patients were included having the history of chronic HCV infection. Of these, 40 per cent (80 patients) were women, and 60 percent (120 patients) were men. The mean age of patients was 47.25 years. In 56 per cent of the patients, diabetes mellitus was seen, and it was 28 per cent proportionally. In 30 cases with a good family history, representing 53.57 per cent of the total, signs of diabetes mellitus were seen. The significant p-value was 0.001. In the 14 patients, BMI<25kg/m2 was seen, while in the 42 patients, BMI >25 was seen. Conclusion: Type II diabetes mellitus has been documented frequently in HCV patients already diagnosed. It is Also contributing to a strong association of type II diabetes mellitus with the positive or any previous family history and an increased BMI above 25.

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