::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

RISK FACTORS AND CLINICAL CHARACTERISTICS OF DEEP VENOUS THROMBOSIS IN THE PATIENTS HAVING GYNECOLOGICAL MALIGNANT TUMOR

AUTHORS:

Dr Muhammad Ijaz, Dr Raheel Inayat, Dr Javeed Abbas

ABSTRACT:

Objectives: The aim of this research work was to find out the risk factors and clinical characteristics of DVT (Deep Venous Thrombosis) in the patients suffering from gynecological malignant tumor, to facilitate the gynecologists for the prevention of the fatal complication. Methodology: The patients suffering from gynecological malignant tumor got treatment in RHC Fazilpur Rajanpur from June 2016 to August 2020, were retrospectively reviewed. Clinical information of the patients including age of the patient, stage of tumor, adeno-carcinoma, time of surgery, type of surgery, hypertension, diabetes, hyperlipemia, CHD (Coronary Heart Disease), chemotherapy, radiotherapy, total stay in hospital and post-operative rehabilitation exercise were gathered for analysis of the clinical traits of patients and to find out the different risk factors of deep venous thrombosis. Results: In this research work, there were sixty-seven patients in the Deep Venous Thrombosis group and five hundred and fifty-four patients were in the non- Deep Venous Thrombosis group. We found a significant difference in the hypertension, age, hyperlipemia, time of operation, adeno-carcinoma, stage of tumor, radiotherapy and post-operative rehabilitation exercises in the participants of non- Deep Venous Thrombosis and Deep Venous Thrombosis group (P<0.050). But there was no important difference in the sex, CHD, stay at hospital and surgical treatment (P>0.050). In the multivariate analysis, various factors including hypertension, age, adeno-carcinoma, hyperlipemia and radiotherapy were the independent risk factors, whereas the protective factor for the Deep Venous Thrombosis was rehabilitation exercise. Conclusion: The patients suffering from gynecological malignant tumor, the screening of Deep Venous Thrombosis should be given due significance, particularly for the patients with elder age, hyperlipemia, hypertension, adeno-carcinoma, or the past history of the radiotherapy. There should be encouragement of the rehabilitation exercise in such patients. KEYWORDS: Deep Venous Thrombosis, malignant, gynecology, adeno-carcinoma, rehabilitation, radiotherapy, Coronary Heart Disease.