::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO DETERMINE THE DEMOGRAPHIC CHARACTERISTICS, OUTCOMES AND CLINICAL PICTURE OF NEONATAL TETANUS

AUTHORS:

Dr Safia Akhtar, Dr Tayyaba Sohail, Dr Muhammad Ali

ABSTRACT:

Purpose: To determine the demographic characteristics, clinical profile and outcomes of neonatal tetanus. Study design: A case series. Place and duration: In the Pediatric Unit-II of Holy Family Hospital, Rawalpindi for one-year duration from April 2019 to April 2020. Material and methods: The study included records of patients with a clinical diagnosis of neonatal tetanus meeting the standard case definition. Data from the patient files were recorded on the proforma. Data were analyzed using an appropriate statistical test. A p value of <0.05 was considered significant. Results: Data from 394 patients were analyzed. The mean age and body weight at the time of reporting were 8.99 ± 4.54 days and 2.77 ± 1.27 kg, respectively. There were 270 males (68.5%) and females 124 (31.5%). The majority (77.92%) were delivered at home and on an untrained podium. Three hundred and forty-six mothers (87.82%) were unvaccinated, while 12.8% were partially vaccinated against tetanus. The most common symptom was the jaw lock (84.26%) and spasm (88.57%). Total mortality was 29.19%, while 54.31% of patients improved and were discharged home. In mechanically ventilated patients, the mortality was 21.5%. Preterm babies with tetanus fared the worst, 98.4% died out. Conclusion: Neonatal tetanus (NT) remains a major health concern and a major contributor to infant and infant mortality in Pakistan. Unimmunized mothers, home deliveries, and cutting the umbilical cord with unhygienic instruments were the main contributors to neonatal tetanus. Keywords: tetanus, presentation, result.