::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

News Updates Latest Volumes: COSMOS IMPACT FACTOR (2018)- 4.153, GLOBAL IMPACT FACTOR(2014) - 0.384, (2015) - 0.437, Indo American Journal of Pharmaceutical Sciences,

ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

A DESCRIPTIVE STUDY ON THE EFFECTS OF THROMBOLYTIC THERAPY IN THE PATIENTS OF MYOCARDIAL INFRACTION

AUTHORS:

Muhammad Bilal Alim, Abrar Maqbool, Asad Maqbol

ABSTRACT:

Objective: The aim of this study is to minimize the response reperfusion time through the administration of drugs – Thrombolytic Therapy. Material and Methods: This study was conducted at DHQ hospital Sargodha and the duration on this study was from January 2020 to October 2020. Initially patients were brought to the hospital by Rescue 1122 service to reach the hospital emergency department (ED) in time. Secondly, emergency CPU was given task to carry out reperfusion with drug administration. A specific form intended for the information of patients was filled for each subject. The form included the information such as thrombolytic therapy, door-to-needle time, reperfusion criteria and complications observed. The groups were compared and a p value <0.005 was declared statistically significant. Results: To analyze the objective, 200 patients were selected. 15 were brought in to emergency department by Rescue 1122 service whereas the rest reported at their own. The average age of the patient was 51 years. Among 200 patients, 140 were males. The patients were provided reperfusion through drug administration – Thrombolysis at CPU (8.21%), CCU (72.20%) and emergency department (13.44%). door-to-needle time was considerably minimized in Chest Pain Unit (CPU). EMS had a minimum total time with p value = 0.0001. Conclusion: The total time had significantly reduced by using the emergency rescue services (EMS) of 1122, The door-to-needle time was set to an acceptable level by formulating the CPU at the hospital emergency department. The reduction in thrombolytic therapy and door-to-needle time will surely result in low perfusion time with thrombolytic therapy. The formation of such Chest Pain Units and efficient medical services is strongly recommended at all local health care facilities. KEYWORDS: Door-To-Needle Time, Thrombolytic Therapy, Reperfusion, Fibrinolytic Therapy.