::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

COMPLETE GERIATRIC EVALUATION AND QUALITY OF LIFE AFTER LOCALIZED PROSTATE CANCER RADIATION THERAPY IN THE AGED POPULATION

AUTHORS:

Dr Areeba Saleem, Dr Ghania Shafqat, Dr Mehak Ali

ABSTRACT:

Aim: Radiotherapy can decrease personal satisfaction for prostate disease patients. Our target was to assess the impact of radiotherapy on QoL in men matured 77 years or more seasoned treated with radiotherapy for a confined prostate disease, and to distinguish indicators of diminished QoL. Methods: We provisionally managed a battery of tests to screen 100 elderly patients for geriatrics, toxicity and quality of life before and two months after prostate disease radiotherapy (NCT 02876239). Patients aged 77 years who had undergone radiation therapy for the correction of confined prostate disease with or without treatment of androgenic difficulties (ADL) were qualified for inclusion in the study. Links between the quality of life of the patients surveyed and tumor attributes, radiotherapy treatment or, on the other hand, CGA limitations were investigated using Fisher's or Mann and Whitney's tests. Changes in the long-term quality of life limits were dissected using the Wilcoxon's test on the marked position. Our current research was conducted at Sir Ganga Ram Hospital, Lahore from March 2019 to February 2020. Results: At the time of the study, scores for IADL disabilities were available in 53% of cases, decreased independence in daily life exercises in 17% of cases, psychological hindrance found in 23% of cases, gloom related to radiotherapy may decrease personal satisfaction of patients with prostate malignancy. Our objective was to evaluate the impact of radiotherapy on quality of life in men aged 75 years or older, treated with radiotherapy for confined prostate disease, and to distinguish indicators of decreased quality of life. Patients and strategies We provisionally monitored a battery of tests for geriatric screening (MNA, GDS, Get up and Go Test, CIRSG, ADL, IADL, MMSE), toxicity (IPSS; IIEF 5), and quality of life (QLQ C30) in 100 elderly patients before and two months after radiotherapy for malignant prostate disease (NCT 02876237). Patients aged 75 years who had undergone radiation therapy with a treatment plan for a limited malignant prostate, with or without treatment of androgenic difficulties (ADL), were qualified for inclusion in the study. Links between the understanding of the quality of life studied and the qualities of the tumor, radiotherapy treatment or CGA limitations were investigated using Fisher's or Mann and Whitney's tests. The changes in the quality of life limits over the long term were analyzed using the Wilcoxon test on the marked position. Conclusion: Notwithstanding some of the time extraordinarily lessened oncogeriatric boundaries, prostate disease radiotherapy was commonly very much endured in these older patients. We found no prescient factor to figure out which patients would encounter hindered personal satisfaction following radiotherapy. Keywords: Geriatric Evaluation, Localized Prostate Cancer Radiation Therapy.