v ::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::
ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

EFFECTS OF CURCUMIN ON CARDIOVASCULAR RISK FACTORS IN OBESE AND OVERWEIGHT ADOLESCENT GIRLS: A RANDOMIZED CLINICAL TRIAL.

AUTHORS:

Dr Syeda Faiqa Batool Bukhari,Dr Deeba Yousaf,Dr Aqsa Baloch.

ABSTRACT:

Introduction: The risk of developing cardiovascular risk and obesity for obese teens is higher in adult life. Dietary intake as an active ingredient of turmeric extract of antioxidants particularly curcumin may have noticeable implications for obesity and its essential complications, including cardiovascular risk factors. The goal of this research was therefore, to determine cardiovascular risk factors in overweight and obese adolescents with the effects of curcumin supplementation. Methods: Fifty girls [aged 18 years] got placebo or intervention randomly. The teenagers were required to eat a standardised 95% turmeric extract or a placebo-containing one 500 mg pill daily, and to retain weight or a moderate weight loss diet for 10 weeks. The baseline and the conclusion of the intervention is measured with anthropometric and biochemical indexes. Results: The body's mass index [P=0.019], waist circumference [P=0.007], hip circumference [P=0.028], high density ratios of lipoprotein [P=0.046], and triglyceride/high density ratio of lipoprotein [P = 0.022] have positive results on curcumin supplementation. In univariate covariance study, however after 10 weeks of supplementation there have been no major variations between the intervention and placebo groups [P>0.05]. Conclusion: Prescription of curcumin supplements together with the implementation of a light weight loss diet may beneficially influence many overweight and obese women's cardiovascular risk factors. Larger clinical trials are required to validate the findings of the current research, with higher curcumin doses and longer duration.

FULL TEXT

<
Top
  • Follows us on
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.