::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

News Updates Latest Volumes: COSMOS IMPACT FACTOR (2018)- 4.153, GLOBAL IMPACT FACTOR(2014) - 0.384, (2015) - 0.437, Indo American Journal of Pharmaceutical Sciences,

ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

TO DEFINE THE RELATIONSHIP OF CLINICOPATHOLOGICAL PATTERN WITH BREAST CANCER IN TERTIARY CARE HOSPITALS; AN OBSERVATIONAL STUDY

AUTHORS:

Dr Muhammad Awais Iqbal, Dr Kiran Shahzadi, Dr Hafiz Zeeshan Muzaffar

ABSTRACT:

Objective: The purpose of our study was to define the relationship of clinicopathological pattern with breast cancer and about the stage, age, histological type, receptor status and tumor grade. Study design: An observational study. Place and duration: This study was conducted at Department of Surgery in Holy Family and Benazir Bhutto Hospital, Rawalpindi for the duration of six months starting from April, 2020 to September, 2020. Methodology: After obtaining informed consent, we include 500 patients of breast cancer for diagnosis, which either treated or referred in Oncology department of surgical treatment for neoadjuvant or adjuvant therapy. We used questionnaire for interview of the patients. For triple diagnosis and related investigations staging was carried out and for receptor status ER, PR, and HER2 new receptors and for histological type, grade, margin clearance we obtained histopathological reports from patients. SPSS version 20 was used for analysis of collected data. Results: In this study we include 500 patients of breast cancer who were aging from 23 years to 80 years. Breast cancer was found most common in up to 57% patients among the age group of 40-50 years. Advanced breast cancer stage III and IV was observed in 64% patients. The most common pathological type was invasive ductal carcinoma observed in 93% patients. Histopathology test results showed that most of breast cancer patients (55%) were having grade II tumors. Conclusion: According to the findings of our study the most common pathological type was invasive ductal carcinoma observed in 93% patients. Histopathology test results showed that most of breast cancer patients (55%) were having grade II tumors. Advanced breast cancer stage III and IV was observed in 64% patients. Therefore, it is very necessary to educate our people about breast cancer and special steps should be taken for screening of it. Keywords: Invasive Ductal Carcinoma, Delayed Presentation, Breast Cancer.