::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

STUDY TO REVEAL THE IMPORTANCE OF 50-G GLUCOSE CHALLENGE TEST FOR DIAGNOSING GESTATIONAL DIABETES

AUTHORS:

Dr. Rabia Batool, Dr Kiran Shahzadi, Dr Marwah Mahmood

ABSTRACT:

Introduction: Gestational diabetes (GDM) is important for public health, in addition to its direct impact on mother and child. Pregnancy is a diabetic condition and is one of the main causes of the GDM type 2 diabetes epidemic. About 1% - 3% of pregnant women will show glucose intolerance. DMG is the most common metabolic complication that affects a pregnant woman. The frequency of GDM and associated maternal, prenatal and long-term morbidity highlights the importance of detection. Aim: To investigate the role of the 50-g glucose challenge test in detecting gestational diabetes. Place and Duration: The study was conducted in the Obstetrics and Gynecology department of Aziz Bhatti Shaheed Teaching Hospital Gujrat for one year duration from 1st May 2019 to 30th April 2020. Method: Two hundred and fifty prenatal patients between 24 and 28 weeks of gestation were tested for gestational diabetes using an oral glucose 50 g load test. Plasma glucose was found to be positive at 130 gm / dL or more, followed by glucose tolerance test (GTT 100 gm: 3 hours). Those with risk factors but negative GCT at 24-28 weeks were again screened at 32 –34 weeks. Normal patients and patients diagnosed with gestational diabetes were compared in terms of risk factors, clinical examination, special and routine tests, and pregnancy outcomes. Results: out of 250 patients, 150 had no risk factors and 100 had one or more risk factors. 10 patients (4%) were diagnosed with gestational diabetes. Eight patients were identified from the group of risk factors after 24-28 weeks and 2 patients after 32-34 weeks. Conclusion: Universal testing of all pregnant women for 24-28 weeks with glucose challenge test is a simple, useful, inexpensive and easy to organize tool for identifying women with GDM. In Pakistan, we recommend universal screening for all pregnant women, because there are 11 times the risk of glucose intolerance compared to white women during pregnancy.