::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

THE OCCURRENCE OF CELIAC DISEASE IN NUTRITIONAL ANEMIA PATIENTS; A CROSS SECTIONAL STUDY

AUTHORS:

Dr. Mah Mobeen Fatima, Dr. Momina Shafique, Dr Zainullah

ABSTRACT:

Objectives: The aim of our study was to find out the occurrence of celiac disease in nutritional anemia patients. Study design: A cross sectional study. Time and duration: This study was conducted in Medical department, Ayub Teaching Hospital Abbottabad for the duration of eight months starting from 1st January, 2020 to 31st August, 2020. Methodology: In this study we included a total number of 100 patients who were diagnosed with nutritional anemia. Hematologic work completed such as peripheral smear, blood complete picture (Blood CP), folate, iron and B12 levels. By gender distribution, Anemia defined in male is Hb <13 g/dL and Anemia defined in females is <12 g/dL. In this study nutritional cases like folate, iron or shortage of B12 in minor anemia cases were included and then the Anti-tissue transglutaminase antibody (anti tTG) antibody testing was carried out. The Anti-tissue transglutaminase antibody (anti tTG) antibody had taken for those cases which tested positive by Jejunal biopsy. We established a Celiac disease (CD) for the diagnosis of histopathology in the behalf of positive findings. A pre- designed proforma was used for the collection of data. SPSS v.20 was used for the analysis of collected data. Results: According to the study the frequency of celiac disease was in 12 patients. According to the findings of our study there were 10 positive cases of Iron Deficiency Anemia (IDA) out of 12 celiac disease patients. From the remaining two patients, one patient presented concomitant B12 + folate deficiency and one patient showed dimorphic anemia. Conclusion: In our study we concluded that in Pakistan 12% of Pakistani may be found in Celiac disease who present nutritional anemia. Consequently, those patients should be tested for celiac disease who do not respond for standard anemia. Keywords: Celiac Disease (CD), Iron Deficiency Anemia (IDA), Anti-Tissue Transglutaminase Antibody (Anti-tTG).