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TITLE:

STUDY OF TWO KILLING DISEASES: HEPATITIS B (HBV), HEPATITIS C (HCV), PREVALENCE AND RISK FACTORS IN RURAL AREAS OF PUNJAB

AUTHORS:

Dr Hafiza Ameema Saleem, Dr Umeroman, Dr Huma Hussain Mughal

ABSTRACT:

Objective: The objective of this prospective study was to examine the risk factors that cause HBV and HCV and their prevalence, evaluating sex and gender as well. Study Design: Descriptive Place and Duration: The study was conducted on the rural area patients of Punjab attending Sir Ganga Ram hospital Lahore. Study was carried out for period of 8 months from 1st Febraury 2020 to 30th September 2020. Method: A total of 900 chronic liver failure patients were enrolled in this study. Detailed demographics of patients were recorded after written consent was adopted. The causes of hepatitis B and hepatitis C viruses were examined for frequency and risk factors. Complete data was analyzed by SPSS 24.0 version. Results: In this detailed study we included 900 patients of liver diseases, Out of 900 We found 150 patients had both Hepatitis B (HBV) and Hepatitis C (HCV), 63 (7%) patients were found +Hepatitis C and 87 (9.7%) patients were found +HBV. The mean age calculated was 37.25 years. In 150 patients of HBV and HCV, men were 60 (40%) and 90 (60%) were women while 25 patients were aged of <18 years. We observed most frequently Hepatitis B and C in the patients between ages of 20 to 35 years (48 (55.17%) patients of HBV and 35(55.55%) patients of HCV viruses respectively). We found most prevalence in women (HBV infection women 51(56.7%) and 39(47.3%) women had HCV). In this study we also included the detailed history of patients such as age, sex, socio-economic status, literacy, poverty, used of pipe lined water or pumped water, smoking history, use of drugs with used injection, blood donation history and organs transplantation history. Conclusion: We found that the frequency of these two killing infections in this study is too high for HBV and HCV compared to other developed countries. These viruses have mostly affected women and adults. Keywords: Factors, HBV C, Hepatitis B, Frequency, Rural Areas.

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