::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

News Updates Latest Volumes: COSMOS IMPACT FACTOR (2018)- 4.153, GLOBAL IMPACT FACTOR(2014) - 0.384, (2015) - 0.437, Indo American Journal of Pharmaceutical Sciences,

ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

COMORBIDITY FACTORS AND BRAIN MECHANISMS LINKING CHRONIC STRESS AND SYSTEMIC ILLNESS

AUTHORS:

Dr. Ahmad Hassan, Dr. Surakshya Ghimire, Dr. Rafat Rasheed

ABSTRACT:

Introduction: Definitions of stress including its explanation. It contains damages on patients suffering from chronic stress along with systemic illness. It mainly destroys sufferer’s nervous system. It causes abnormal transmission of signals from nervous system to other body parts causing them to pass severe conditions. This article explains the destruction of stress and systemic illness on psychiatric health of patients.[1] Effects: The major impacts of stress and systemic illness are shown in structure and functions of nervous system. It affects CNS as a whole, particularly mood-regulating parts of brain such as hippocampus and PFC. Experimental analysis of stresses humans and other animal models indicate the similarities such as cell discharge, decreased tissue density.[1] Disorders: Particular disorders such as neurological illness, SUD along with alcoholism, stroke, Alzheimer’s disease, cardiovascular disease (CVD), gastrointestinal disease, obesity along with metabolic illness are major disorders caused due to chronic stress and systemic illness. They have worse impacts on the psychological health of patients.[1] Treatment: Pulmonary renewal and daily exercise can reduce the complications, additionally it enhances the patient’s humour. It also increases the number of mitochondria in particular muscles. Several specific masculinization of medications can help in reducing stress, additionally these help to normalize the patient’s condition. Inhaled therapy is also used as the cure method.[2] Conclusions: Behind each psychiatric illness, the main cause is stress and systemic illness. Stress is one of the foremost prevailing psychiatric diseases. Extensive observations are needed to save the mental health of patients.[1]