Dr M Raza, Dr Sehreen Anmber, Dr Ayesha Munawar
Objective: This exploration of work conceded to evaluate the prevalence of the post-surgical infection, fracture nonunion and different risk factors responsible for infection in the positive patients of HIV (Immunodeficiency Virus). Methodology: We compared the prevalence of the post-surgical infections and fracture nonunion between the patients of both groups, we also evaluated the risk factors for the infections after surgery in the positive HIV patients. We retrospectively evaluated the HIV positive patients suffering from fracture treated with surgery in Orthopedic Department of Sir Ganga Ram Hospital, Lahore from December 2015 to October 2018. We also selected 50 more patients as controls that were present with fractures but they were negative HIV patients. We reviewed the clinical information of the patients of both groups. Results: We found no important disparity in the nonunion rate between the patients of both groups (P >0.050).The prevalence of the adverse healing of wound and incision infection in group of HIV positive patients was much high as compared to the group containing negative HIV patients but there was no significant disparity between the patients of both groups (P >0.050). Multivariable regression examination showed that HIV medical category (P <0.050), category of CD4+T-lymphocyte (P <0.010) and open fracture (P <0.050) were the common risk factors for the wound infection after surgical intervention but age, sex, duration of surgery, type of incision, emergency operation, count of albumin & lymphocyte were not the significant risk factors (P >0.050). Conclusion: There can be healing of the incision and there can be unity of the fracture in majority of the positive HIV patients present with fracture. There was close association of the infections of wound after surgical intervention with the open fracture, category of CD4+ lymphocyte and HIV medical category. Keywords: Infection, wound, surgery, albumin, HIV, intervention, prevalence, methodology.