::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

HISTOLOGICAL DIAGNOSED CASES OF ADENOMYOSIS AMONG CLINICAL DIAGNOSED CASES OF ADENOMYOSIS AT A TERTIARY CARE HOSPITAL

AUTHORS:

Dr. Mehreen Naz, Dr. Eram Najm, Dr. Bushra Ishtiaq

ABSTRACT:

Introduction: Adenomyosis is a condition where there is aberrant location of endometrial glandular tissue within the uterine myometrium and is often associated with cyclical uterine pain, dyspareunia, abnormal uterine bleeding such as menorrhagia, spotting or bleeding before and after menses, and infertility. The prevalence of adenomyosis differ from 5 to 70 %, with the mean frequency of adenomyosis at hysterectomy given as approximately 20 to 30 % (Yu et al., 2020). The frequency of adenomyosis keep on rising as age of the patient increases, peaks between 40-50 years of age and then reaches a plateau after menopause. Methodology: Setting: The study was conducted in the Gyneacology and Obstetrics department of Sir Gangaram Hospital Lahore Duration: The duration of the study was nine months. Study Design: Analytical cross-sectional study. Sampling Technique: Non-probability consecutive sampling. Data Collection The histological specimen of clinically diagnosed adenomyosis was done microscopically by the pathology department of sir gangaram hospital Lahore by examining small tissue samples of the uterus. These tissue samples were collected from a uterine biopsy or directly following a hysterectomy. Uterine biopsies were obtained by either a laparoscopic procedure through the abdomen or hysteroscopy through the vagina and cervix. Histopathological image of uterine adenomyosis was observed in uterus specimen using the hematoxylin & eosin stain. Results: A total of 87 hysterectomy specimens studied had adenomyosis as microscopic findings. The patients ranged from 25 to 75 years with average 43 years of age. Majority of the cases were between 40-50 years,52/87(59.8%). Abnormal uterine bleeding was the most common symptom seen in 47 patients (54%) followed by prolapse in 16 cases (18.4%).