::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A PROPORTIONAL ANALYSIS OF EFFECTIVENESS FOR TOCOLYSIS OF PRETERM LABOUR BETWEEN NIFEDIPINE AND MAGNESIUM SULPHATE

AUTHORS:

Dr Saima, Dr. Muhammad Hasnain, Dr Wahab Nasir

ABSTRACT:

Objective: The objective of this evaluation and research was to weigh up the effectiveness of nifedipine and magnesium sulphate for tocolysis of preterm labour. Materials & Methods: We concluded this proportional research in the period of November 2017 to December 2018 at Mayo Hospital, Lahore on 182 patients. These patients were categorized as preterm labour patients. The age bracket of the patients was from 16 years to 35 years. LMP evaluated gestational age was (28 – 36) weeks with a singleton pregnancy. We did not include any patients under the age of 16 years and above the age of 35 years along with those patients who presented history of pre-eclampsia, diabetes mellitus, hepatics function, cardiac disease, severe IUGR, membranes rupture, ante partum hemorrhage, fetal distress, cervix (>4cm) dilated, chorioamnionitis, congenital fetalmal formations, multiple pregnancies, nifedipine allergic and Salbutamol allergic. Conclusion: The conclusion shows that higher effectiveness can be obtained through magnesium sulfate (89.1%) forpreterm labour (acute tocolysis) than oral nifedipine. Keywords: Magnesium Sulfate and Oral Nifedipine, Tocolysis Agents, Preterm Birth, Uterine Contractions.