::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

EXAMINE THE FREQUENCY OF ACUTE RENAL FAILURE IN PATIENTS WITH PARAPHENYLENE DIAMINE POISINING

AUTHORS:

Dr Muhammad Junaid Qasim, Asad Rahman, Dr Muhammad Zeshan

ABSTRACT:

Objective: Determination of the frequency of acute renal failure in paraphenylene diamine (PPD) poisoning patients. Study Design: Retrospective/Observational Place and Duration: The study was conducted in Bahawal Victoria hospital Bahawalpur and Sheikh Zayed Hospital, Rahim Yar khan for duration of one year from May, 2019 to April, 2020. Materials and Methods: This study enrolled a total of 100 patients of both sexes who received paraphenylene poisoning. Detailed demographics were recorded age,sex and reasons for ingestion of PPD. Clinical presentation has been recorded, including signs and symptoms. Frequency of acute renal failure was examined by serum creatinine mg/dl. Data was analyzed by SPSS 24.0. Results: Out of 100 patients 78 (78%) were females while 22 (22%) were males. The mean age of patients was 23.98±7.68 years. Suicide was the most common reason for poisoning of PPD found in 92 (92%) cases. Cervico-facial edema was the commonest symptom found in 90 (90%) patients. Acute renal failure was observed in 80 (80%) patients. From 80 acute renal failure patients 76 (95%) were recovered after treatment while 4 (5%) patients had residual renal damage. Conclusion: It is concluded that the frequency of acute renal failure was very high in patients with paraphenylene diamine poisoning, but rapid medical treatment helps reduce morbidity and mortality.. Keywords: Acute Renal Failure, Paraphenylene Diamine Poisoning.