::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

TO ASSESS THE RELATIONSHIP AMONG HEART RATE, BLOOD PRESSURE AND LIPID PROFILE IN CLINICAL HYPOTHYROIDISM; A COMPARATIVE STUDY

AUTHORS:

Dr Muhammad Furqan Hashmi, Dr Sadam Hussain, Dr Muhammad Shakir Ashraf

ABSTRACT:

Objective: The aim of our study was to assess the relationship among heart rate, blood pressure and lipid profile in clinical hypothyroidism. Study Design: A comparative study. Place and Duration: This study was conducted at the Department of Physiology, Bahawal Victoria Hospital Bahawalpur for the duration of seven months starting from February, 2020 to September, 2020. Methodology: In our study selection of patients were done by non-probability purposive sampling. On the basis of thyroid profile, the patients were divided into two groups naming, case (clinical hypothyroids) and control (euthyroids). Clinical measurement for vital parameters like blood pressure, laboratorial evaluation and heart rate was systematically analyzed. Results: A very important statistical connotation was found in triglyceride, serum cholesterol and surface lipoprotein low density (calculated probability was less than 0.01). Similarly, a statistically significant relationship was found between maximum heart rate (the calculated probability was equal to 0.03) and normal heart rate (the calculated probability was equal to 0.02). Furthermore, a very important statistical relationship between the two study groups was found in systolic, mean arterial blood pressure and diastolic blood pressure (calculated probability was less than 0.01). Conclusion: At the end of the available data suggest that, even mild forms of treatment for heart risks, early diagnosis, and functional thyroid disorders may be beneficial in the vast majority of patients. Yet, overtreatment should be avoided and individual variances of age-related or pituitary thyroid set points must be respected. Clinical hypothyroid patients are in extraordinary risk of pro-atherogenic lipid abnormalities and hypertension. Keywords: Tri-Iodothyronine, Hyperlipidemia, Blood Pressure, Heart Rate, Hypothyroidism, Thyroid Stimulating Hormone.