Christal C*, Savitha Mol G.M, Dr. Silvia Navis, Dr. Prasobh G.R.
Diabetes Mellitus(DM) is a metabolic disorder characterized with insulin deficiency or due to insulin resistance. Macrovascular and microvascular complications are the major causes of mortality and morbidity in diabetes patient. During Hyperglycemia condition, oxidative stress and increase lipid peroxidation are due to free radical’s formation which have a main role in diabetic complications. Therefore, antioxidants act against an oxidative stress that can prevent tissue or cell damage induced by free radicals. Antioxidants in fruits, vegetables, and grains helps to prevent the diabetes complications. There is some evidence regarding prevention of cell or tissue damage is that taking antioxidants substance can protect diabetes complications. The main objective of given review is regarding a role of antioxidants for the prevention and treatment of diabetes complication. Keywords: oxidative stress, antioxidant, diabetes mellitus, hyperglycemia, free radical.