::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

TO REVEAL FREQUENCY OF FATTY LIVER IN PAKISTAN COHORT WITH RHEUMATOID ARTHRITIS

AUTHORS:

Dr Amir Hussain, Dr Iqra Jamil, Dr Usman Raza

ABSTRACT:

Objective: To determine the frequency of fatty liver in Pakistan cohort with rheumatoid arthritis. Study Design: Cross-Sectional Place and Duration: This study was conducted at Mayo Hospital, Lahore for a duration of ten months from 1st November, 2019 to 31st August, 2020. Methods: 200 patients were included in this study. Patients detailed demographics age, sex, body mass index, smoking habits were recorded after taking written consent. The abdominal ultrasound scan was carried out by a radiologist. On the next day, 10 ml of blood was taken by the phlebotomist for lipid profile and fasting blood sugar levels, and 10-year Framingham cardiovascular risk score was calculated after results were available. Complete data was analyzed by SPSS 24.0 version. Results: Total 165(82.5%) were females presented in this study with mean age of 43.2 years. Fatty liver was observed in 45(22.5%) patients. Frequency of metabolic syndrome was in 33(73.33%) patients, diabetes mellitus was in 15(33.33%) patients, hypertension was in 26(57.8%), FRS score at high in 16(35.5%), previous history of desi medication was in 24(53.33%), While all study parameters except DMARDs were significantly associated with fatty liver during regression analysis (p<0.05). Conclusion: We concluded that non-alcoholic fatty liver disease is very prevalent in rheumatoid arthritis patients. As in the general population, it is multifactorial in origin, and needs careful monitoring and treatment. Keywords: MeTs, MARD’s, FRS, Fatty liver, RA.