::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A COMPARATIVE STUDY BETWEEN ST- ELEVATION ACUTE MYOCARDIAL INFARCTION IN DIABETIC AND NON-DIABETIC PATIENTS

AUTHORS:

Dr Faiqa Sarwar, Dr Muhammad Abu Bakar Siddique, Dr Muhammad Talha

ABSTRACT:

Objective: To compare transmission, control of disease and some other aspects between the patients of diabetes and non-diabetic people admitted with ST- segment elevation acute myocardial infarction (STEMI). Material and Method: This study was conducted at Ganga Ram Hospital Lahore and the duration of this study was from January 2020 to December 2020. The total number of participants in this study was 240. 70 were the patients of diabetes and 164 were non-diabetic. Results: 11 patients among diabetic patients were recently detected. Female to male ratio in the diabetic disease was 1:1.5 but female to male ratio in the non-diabetic participants was 1:5.8. ST- segment elevation acute myocardial infarction was observed in high rates in the patients of diabetes than non-diabetic patients at the age from 55 tears to 64 years. 82% patients reported at hospital within 6 hours of the start of the pain in the chest. About 53% were smoking from many years, 40% patients found with fully established dyslipidaemia, about 33% patients were fat, 32% patients were suffering of diabetes and 29% were the cases of hypertension. An important amount of the non-diabetic patients was smoking from many years but an important percentage of the diabetic patients were fat. Dyslipidaemia was concluded as a major danger factor in the patients of diabetes but it was at number three in the case of non-diabetic patients. The sideways infarction was much frequent in the patients of diabetes. The level of Trop-T was less in 46% and high in 54% patients of diabetes. The level of Trop-T was found negative in 10%, discoverable in 3%, less in 39% and high in 48% non-diabetic patients. The average amount of different enzymes did not present any disparity between the patients of diabetes and non-diabetics as Trop-T, CK and CK-MB. The average duration spent by the patients in the hospital was about 5.99±1.04 days. Conclusion: Fatness, smoking, dyslipidaemia were the major danger factors of ST- segment elevation acute myocardial infarction. The most common site is anterior Infarction. In the patients of diabetes, the probability of ST- segment elevation acute myocardial infarction is similar in men and women but in the non-diabetics it is six men to one woman. Key Words: Acute Myocardial Infarction, Diabetes, Danger Aspects, Dyslipidaemia.