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TITLE:

THE RISK OF CARDIOVASCULAR DISEASE AND THE IMPACT OF HYPERGLYCEMIA ON TYPE 1 DIABETES RELATED CVD MORTALITY

AUTHORS:

Maryam Javed, Dr Noor ul Ain Fatima, Mahum Ijaz

ABSTRACT:

Aim: Think regarding the risk of cardiovascular disease (CVD) and the impact of hyperglycemia on the risk of type 1 diabetes-related CVD mortality on type 2 diabetes. Methods: The inquiry involved 177 participants with type 1 diabetes, 839 members with type 2 diabetes and 1,294 non-diabetic members, aged 47–65 years at the gage and released from CVD. Our current research was conducted at Mayo Hospital, Lahore from May 2019 to April 2020. The time of onset of diabetes was 32 years in both diabetic meetings. Results: During the 18-year period, 86 members with type 1 diabetes, 569 members with type 2 diabetes and 252 non-diabetic members kicked the bucket. CVD mortality rates per 1,000 man years is 23.1 (95 per cent CI 16.9 – 31.9) for diabetic grade 1, 36.4 (31.9 – 41.5) for diabetic grade 2, and 5.7 (3.9 – 5.8) for non-diabetic participants. Changes in the probability of CVD death is 3.6 (95 per cent CI 2.2–5.7) in males and 14.4 (6.9–24.6) in females and participants of type 2 diabetes versus no 3.3 (2.5–4.5) in males and 12.2 (7.8–18.5) in females. A rise of 1 unit (percent) of GHb improved CVD mortality by 53.6 per cent (96 per cent CI 28.6–82.4) in diabetic subjects of type 1 and 8.6 per cent (4.3–12.9) in diabetic subjects of type 2. Conclusion: The effect of type 1 and type 2 diabetes on CVD mortality was comparative. The impact of expanding hyperglycemia on the danger of CVD mortality was more significant in sort 1 than in kind 2 diabetic subjects. Keywords: cardiovascular disease (CVD), impact of hyperglycemia, risk of type 1 diabetes-related CVD, mortality, type 2 diabetes.

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