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TITLE:

EXTREME ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPECIAL ANTIBODY REACTION IN CORONAVIRUS ILLNESS CASES

AUTHORS:

Sidratul Muntaha, Aqsa Khaild, Dr Sania Hussain

ABSTRACT:

Another Covid, Covid 2 (SARS-CoV-2), an extremely intense respiratory disorder, has recently emerged to cause a human pandemic. While atomic indicator tests have evolved rapidly, serological measurements are still lacking, but are desperately needed. Approved serological tests are needed for contact tracing, virus pool recognition and epidemiological investigations. Our current research was conducted at Jinnah Hospital, Lahore from February 2020 to October 2020. We have developed serological tests for the discovery of antibodies to SARS CoV-2, explicit antibodies to peak proteins and explicit antibodies to nucleocapsules. Using serum assays from patients with PCR-confirmed SARS CoV-2 contaminations, other Covid, or other pathogenic respiratory diseases, we have also approved, assayed different antigens in various in-house and commercial ELISAs as well. We have shown that most PCR-confirmed SARS CoV-2 infected individuals seroconverted approximately 14 days after the onset of infection. We found that the IgG or company S1 IgA ELISAs were less specific, and that the affectability varied between the two tests; the IgA ELISAs indicated higher affectability. In general, the approved tests described may be useful for the discovery of explicit antibodies to SARS-CoV-2 in the context of demonstrative and seroepidemiologic antibody evaluation. Keywords: Extreme Acute Respiratory Syndrome, Coronavirus 2–Special Antibody Reaction.

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