::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

RHEUMATOID ARTHRITIS: PATHOPHYSIOLOGY AND IMPLICATIONS FOR THERAPY.

AUTHORS:

Dr Ayesha, Dr Madiha Tahir,Dr Sana Mushtaq.

ABSTRACT:

In 1947, a scholar suffering from rheumatoid arthritis observed the agglutination (blending) of her own serum. It was proposed that this was due to arthritis. A physician worked on it. 70-80% patients suffering from rheumatoid arthritis was observed to have agglutination. Rheumatoid factor serves as a main cause for the disorder. Researches show that there are five stages of rheumatoid arthritis, particularly. All stages have their own certain implication along with analysis. It is observed that there is increase in number of certain cells and molecules in patient suffering from disorder. May be some viruses and antigens are the causes of development of the disease. There are particular chemical analysis and cures for each of these stages. But, as the main cause of disorder is underexplored, so we have a little information about the therapy. In conclusion, rheumatoid arthritis is a cellular immune response, it includes proliferation of some cells along with devastation of articular cartilage.