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TITLE:

TO DETERMINE THE EFFECTIVENESS OF ORAL MISOPROSTOL IN THE INDUCTION OF LABOR

AUTHORS:

Dr Muhammad Ahmed Arif, Dr Ayesha Arif, Dr Noor Fatima Malik

ABSTRACT:

Objective: Labor induction is frequent, lifesaving procedure in almost all obstetrical practice1. Labor induction is a procedure in which labor is started artificially before its spontaneous onset, to accomplish safe delivery of fetus and placenta. Aim of this study was to determine the efficacy of oral misoprostol in the induction of labor at term pregnancy Study Design: This was a Prospective observational study Place and Duration of Study: This study was conducted in Obstetrics & Gynaecology Department of Mayo Hospital Lahore for the duration of one year, from June 2019 to June 2020. Patients and Methods: All women received 50 ug of tablet misoprostol orally every 4 hours (max 6 doses). All the women were followed up regularly till 12 to 24 hours after the first course of 3 doses patients were given 24 rest and then re induced with patient consent. All the observations and therapeutic intervention were done under supervision of an expert obstetrician having minimum of five years of experience. Results: In this study mean age was 27 years with SD ± 2.317. 43 percent patients were Primi gravida patients while 57% patients were multi gravida. The most common indication for induction was postdate pregnancies (41%) followed by PROM and oligohydramnios. 211(95%) patients delivered with 24 hours requiring only 3 doses of misoprostol. The efficacy of misoprostol was found to be 78% in induction of labor at term pregnancy. Conclusion: The efficacy of misoprostol was 78% in induction of labor at term pregnancy. Key Words: Efficacy, Oral misoprostol, Labour induction, Term pregnancy

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