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TITLE:

MULTIFUNCTIONAL EXCIPIENTS: A NEW TREND OF EXCIPIENT TECHNOLOGY

AUTHORS:

Mallela Haritha*, Dubbaka Bhavana, Pallavi Kanagala.

ABSTRACT:

The pharmaceutical industry demands innovation in a short period of time so as to gain the access to new products in market. The major requirement for direct compression process is selection of excipients with optimum physical characteristics which improve the tablet blend’s final flow and compressibility. Co-processed excipient has gain popularity in formulation development of various dosage forms. The goal of this review is to discuss the emergence of co-processed excipients in pharmaceutical manufacturing as a new trend in excipient technology. Co-processing is a novel concept of combining two or more excipients that posses specific advantages. The review discusses about the sources of new excipients, potential advantages, material characteristics, various methods of preparation, description of some available co-processed excipients. Key words: Co-processed excipients, Direct compression, Pharmaceutical manufacturing, Co-processing.

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