::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

THE CROSS-SECTIONAL STUDY OF ASSOCIATION BETWEEN DEPRESSION AND THYROID PROFILE

AUTHORS:

Dr. Ameer Hamza, Dr. Muhammad Zohaib Chaudhary, Dr. Hasnain Ahmed, Rukhsar Javaid, Muhammad Waseem Abbas*

ABSTRACT:

Introduction: Depression is the leading cause of mental morbidity worldwide especially in young population. It is one of the major contributors to the disease burden globally. The high prevalence rate and chronic course of depression have caused significant mental and somatic morbidity and loss of productivity in young generation in either the case that the young person is suffering from depression or his parents. Aims and Objective: To find out the association of thyroid disorders with unipolar and bipolar depression. Materials and Methods: This cross-sectional study was conducted at Nishtar Medical University and Hospital (NMU&H), Multan from September 2018 to October 2018. Total 300 patients with depressive symptoms 159 unipolar and 141 bipolar cases were included. These patients were not taking any medication for at least 1 month prior to the onset of recent episode and gave written informed consent. A minimum amount of 2 ml of venous blood from each subject was required and tests included were T3, T4 and TSH. Results: Regarding thyroid function test, 191 cases were euthyroid among which 69.05 % were females and 59.77 % were males. Conclusion: The study concludes that thyroid function disorders were significantly found in cases of unipolar depression while most of the bipolar cases had normal thyroid status. Key words Depression, Thyroxine, Hyperthyroidism, Unipolar, Bipolar