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TITLE:

THE DANGER OF SERIOUS COVID‐19 IN PATIENTS WITH PRE‐EXISTING PERSISTENT OBSTRUCTIVE ASPIRATORY ILLNESS (COPD) AND CONTINUOUS SMOKING HISTORY

AUTHORS:

Ayesha Nasir, Aalia Saeed, Zarmina Younes

ABSTRACT:

Comorbidities are related with the seriousness of Covid sickness 2019 (COVID‐19). This meta‐analysis expected to investigate the danger of serious COVID‐19 in patients with pre‐existing persistent obstructive aspiratory illness (COPD) and continuous smoking history. A complete precise writing search was conveyed out to discover contemplates distributed from January 2020 to October 2020 from five information bases. The dialects of writing included English and Chinese. The point commonness of serious COVID‐19 in patients with pre‐existing COPD and those with progressing smoking was assessed with this meta‐analysis. By and large 11 case arrangement, distributed either in Chinese or English language with an aggregate of 2002 cases, were remembered for this examination. Our current research was conducted at Jinnah Hospital, Lahore from January 2020 to October 2020. The pooled OR of COPD and the improvement of serious COVID‐19 was 4.39 (fixed‐effects model; 96% CI: 3.35‐9.21), while the OR of progressing smoking was 1.97 (fixed‐effects model; 96% CI: 1.27‐4.06). There was no distribution inclination as inspected by the pipe plot and Egger's test (P = not critical). The heterogeneity of included examinations was moderate for both COPD and progressing smoking history on the seriousness of COVID‐19. COPD and progressing smoking history quality to the more terrible movement and result of COVID‐19. Keywords: COVID‐19, pre‐existing persistent obstructive aspiratory illness (COPD), smoking history.

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