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MANAGEMENT OF ASTHMA IN PRIMARY CARE

Majed Alshehri , Duaa Saeed Alameer , Sarah Mahmoud Shams , Hassan Jawad Alsaad , Mohanad Nabeel Ghazooli , Mohammed Zaki Alzumi , Yahya Ameen Yahya Kurdi , Bashair Adnan Ali Alhabedi , Wail Omar Algorashi , Mousa Sulaiman Ghazwani , Alaa Ahmed Aljohani , Mohammad Ali S Alghamdi , Sarah Ali Bunajimah , Abdulwahab Aali Muslim Almanjumi , Alshafie, Anmar Yahya A

Introduction: There have been great advances in Asthma focused on asthma across the lifespan and reported on some key findings linked to asthma inception, the microbiome, and the epigenome. Additionally, some new aspects of predicting and preventing asthma exacerbations were reported. It is obvious that research advances are being made in many areas related to asthma, like epidemiology, immunology, microbiology, genetics, biomarkers, and new medications, so much so that it is still difficult for those writing asthma guidelines and strategies to synthesize this work and rapidly apply it to clinical practice. So, reviews of key discoveries are important to keep the clinician abreast of these findings, so that they can be considered in the clinical setting while they await integration into asthma guidelines. Recently a study discussed new findings reported in the Journal of Allergy and Clinical Immunology (JACI) and other publications that relate to respiratory tract infections, air quality, factors that influence long-term outcomes, patient-centered outcomes research, precision medicine, and new observations linked to medications and asthma management. Aim of work: In this review, we will discuss asthma. Methodology: We did a systematic search for asthma using PubMed search engine (http://www.ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com). All relevant studies were retrieved and discussed. We only included full articles. Conclusions: There are new advances in the development related to the natural history of asthma and the effect of the environment. No previous era in asthma management that has witnessed the introduction of so many new classes of medications. It is considered a great challenge for doctors and those contributing to asthma guidelines to select relevant pieces of information that should be incorporated into clinical practice. Temporarily, doctors must keep up with these new findings to add benefits to patients by applying strategies that are most likely to be effective. Key words: Air quality, airway hyperreactivity, allergen immunotherapy, allergen sensitization, allergy, asthma, biomarkers, climate, chronic obstructive pulmonary disease.

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