ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

DIAGNOSIS AND MANAGEMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS

Sharifa Salem AlShehri , Raghad Ali Albalwi, Mohammed Ezz Mohammed Basnawi , Faisal mahmoud Barad Turkistani , Saeed Mohammed Saeed Alghamdi , Zainab Mohammed Abdulkarim Al Faraj , Mariam Ali Almalki , Khalid Mohammed F. AlOtaibi , Mona Ahmed Ahmed Al Hamad , Abdulsalam Siddiq Mohammed Arishi , Lama Hassan Ali Saleh , Ali Abdulla Almazeedi , Maha Ibrahim Alqdairi , Sukayna Adil Salman Al Hamad , Moatasem Mohammed Modhish ,Yasser Safar Abdullah Alqahtani

Introduction: Systemic lupus erythematosus (SLE) is considered a chronic autoimmune disease that mainly affects females. It is recognized by a wide spectrum of clinical conditions, but, its course and organ involvement are unpredictable. Though over the last years an enhancement in survival for SLE patients has been found, pathogenic mechanisms causing this disease are under investigation. Comorbidities, due to both disease and treatment, as well as multiple aspects of SLE, are under intensive investigation. There are many reviews and studies on SLE focusing on pathogenesis, clinical and laboratory features, as well as current and new therapeutic strategies published over the last year.Aim of work: In this review, we will discuss Diagnosis and management of Systemic lupus erythematosus Methodology: We did a systematic search for Diagnosis and management of Systemic lupus erythematosus using PubMed search engine (http://www.ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com). All relevant studies were retrieved and discussed. We only included full articles. Conclusions: Systemic lupus erythematosus (SLE) is considered a chronic autoimmune disease that mainly affects females. It is recognized by a wide spectrum of clinical conditions, but, its course and organ involvement are unpredictable. Though over the last years an enhancement in survival for SLE patients has been found, pathogenic mechanisms causing this disease are under investigation. But a major knowledge in the SLE pathogenesis and consequently the implication of therapeutic strategies are still needed to better prevent and cure SLE. Key words: Presentation, diagnosis, management, systemic lupus erythematosus

FULL TEXT