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CLINICAL PROFILE OF PATIENTS WITH ALCOHOLIC LIVER DISEASE

Bedar Bakhat Khan, Dr. Muhammad Sohail Baig, Dr. Tufail Ahmed Baloch, Hamid Nawaz Ali Memon,Dr. Samar Raza and Dr. Ali Raza Shaikh

OBJECTIVE: To determine the clinical profile of patients with alcoholic liver disease PATIENTS AND METHODS: A total of fifty patients with alcoholic liver diseases were included in this study. The criterion for the selection of the patients for the study was those patients with the history of consumption of alcohol of ≥ 60 gm per day for 3 years durations. The exclusive criteria were patients with liver diseases due to non alcoholic causes and patients with alcoholic liver diseases who are found to have other causative factors while the frequency / percentages (%) and means ±SD computed for study variables. RESULTS:During six month study period total fifty patients had alcohol liver disease were explored and study. The mean ± SD for age of population was 50.54±5.942. Duration of alcohol use (yrs) < 5 04 (8.0%), 5-10 13 (26%), >10 33 (66%), residence urban 22 (44%), rural 28 (56%), clinical presentation abdominal pain and swelling 33 (66%), ascites 17 (34%), pedal edema 19 (38%), jaundice 12 (24%), hepatic encephalopathy 11 (22%), mortality 09 (18%). ↓albumin 38 (76%), ↑gammaglobulins 07 (14%), ↑AST 32 (64%), ↑gamma GT 30 (60%), ↑ALT 35 (70%), ↑alkaline phosphatase 10 (20%), ↑PT 37 (74%), ↑bilirubin 09 (18%) whereas the ultrasound findings were liver cirrhosis with portal htn 22 (44%), liver cirrhosis without htn 20 (40%) and enlarge liver 08 (16%). CONCLUSION:Alcoholic liver disease was commonly seen in middle aged males. Clinical, biochemical and histopathological abnormalities revealed various stages of hepatic damage. KEYWORDS:Cirrhosis, Alcohol and Chronic liver disease.

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