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PHYSIOLOGICAL BASES IN DEFINITION OF LEUKOCYTURIA AND ERYTHROCYTURIA

Dr. Shahid Iqbal, Dr.Muhammad Adil Khan, Dr. Muhammad Ali

As a part of leukocyturia and erythrocyturia amount has been utilized to identify renal diseases for a long period. Additionally the observed attributes are the type involving main standards to recognize urinary syndrome. The objective of the research function ended up being to define that the appropriate physiological regimen of kidneys working functioning that enables to fulfill reliability with the circumstances in kidneys along with the blood cells preservation in urine for additional improvement with the urinary disorder symptomatic technique. Generally we reviewed twenty four healthy participants between the age of 19–25 without medical and clinical signs of kidneys pathology. Research work was performed in the screening from 9–11 while on an empty stomach. The overall investigation strategy incorporated the draining of the urinary bladder subsequently hydrosaline loading was performed per os in volume of 0.5 % from the entire body mass. Within an hour determination that individual under the examination emptied his bladder and the volume of diuresis was determined accurately up to 1 ml. They used photometric approach to discover creatinine concentration by Popper’s methodology, also photometric approach was adopted to discover protein quantity as stated by the response with sulfosalicylate acid within the spectrophotometer SF – 46 and urine osmolality applying crioscopic approach on osmometer, model 3D3 expressed by “Advanced Instrument Inc.” (USA). We have additionally accomplished the four-serial examination: with running water loading (1st group) and with natrium chloride solutions loading, 0.1 % (second group), with 0.25 % (third group) and with 0.5 % (fourth group). The attained outcomes were up statistically implementing the Student criteria. The accomplished data established the fact that running water loading and also the 0.1 %, 0.25 %, and 0.5 % natrium chloride solutions loading significantly increase diuretic level and diuresis volume per 1 min is greater than diurnal diuresis level 2 – 3 times with recount for 1 minute. Generally it has been excreted from 25 % up to 90 % of the intoxicated liquid volume. Withal, diuresis amounts do not fluctuate significantly from each other considering all of loading types. That particular is, the recommended by us amount of hydrosaline loading supplies equivalent diuresis surmounting. Approach of diuresis enhance differs significantly: with water loading kidneys are operating in regimen of urine dissolving the thing that is demonstrated by lowering of urine osmolality to the exact level which happens to be typical of blood plasma and below. Urine osmolality of some tested participants was varying between 120 – 200 mosmol/kg. There is no doubt that such a dynamic causes depression of kidney's concentration capability caused by providing an organism with significant amount of running water, osmolality of that will be not more than 5 mosmol/kg. In 0.5% body mass volume the Hydrosaline loading with water and 0.1 %, 0.25 % and 0.5 % solutions of natrium chloride preserves diuresis speed retaining within the volume of 2 – 3 ml per 1 min, however varies in urine osmolality amount. After hydrosaline loading with 0.5 % solution of natrium chloride urine osmolality creates physiologically additional optimal circumstances and might be suggested for leukocyturia and erythrocyturia perseverance. Keywords: Erythrocyturia; Leukocyturia; Urinary syndrome.

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