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CIRRHOSIS AS THE POSSIBLE REASON OF INFLAMMOTORY DISEASES OF A MUCOUS MEMBRANE OF AN ORAL CAVITY AY ORTHOPEDIC PATIENTS

Zhad’ko S.I., Sevbitov A.V., Kushnir K.G., 2Kozhemov S.I., Nikonova A.V.

Relevance of a subject. The most severe form of pathology of a liver – cirrhosis. Cirrhosis takes the 6th place in the general structure of disability, mortality and incidence in economically developed countries. Recently, according to WHO data, there is a continuous increase in chronic diseases of digestive organs and cirrhosis around the world. Research of dynamics of changes of fibrinolitic and proteolytic activity of leukocytes of peripheral blood in washouts which were taken away from an oral cavity from patients with cirrhosis if they have orthopedic designs. Basic provisions. An imbalance in immune and proteolytic systems accompany the course of cirrhosis. Emergence, a current and the result of inflammatory process are influenced by system shifts of key indicators of a fibrinolysis and proteolysis and system shifts of immune potential. The current of a somatopathy can be made heavier by components of acrylic plastic of orthopedic designs and pathological processes in an oral cavity. Conclusions. The relevance of researches which are directed to studying of changes of indicators of a fibrinolysis and proteolysis at orthopedic patients with cirrhosis and need of prevention of inflammatory processes of a mucous membrane of a prosthetic bed are demonstrated by prevalence of diseases of internals. Keywords: cirrhosis, orthopedics, proteolysis, fibrinolysis, inflammation, oral cavity.

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