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MICROEMULGEL AS A NOVEL APPROACH FOR ENHANCING TOPICAL DRUG DELIVERY: A REVIEW

Akashdeep R. Udmale*, Pranav N. Jain, Mukeshkumar V. Choudhary

Topical drug delivery is a localized drug delivery system anywhere in the body through ophthalmic, rectal, vaginal & skin as topical routes. These are apply a wide range of preparations for both cosmetic and dermatological to their healthy or diseased skin Microemulgel have emerged as one of the most intresting topical delivery system as it is a dual control release system i.e gel & emulsion. Both hydrophilic & hydrophobic types of drugs are incorporated into dosage forms. The major objective behind this formulation is delivery of hydrophobic drugs to systemic circulation via skin. Topical drug delivery has the main advantage of direct delivery of the drug to the target tissue i.e. skin & mucous membranes, by passing the first pass effect. Microemulgel with its micron sized globule has better penetration & with gelling property exhibit control drug release. The Microemulgel for dermatological & Cosmetic use have different favorable properties such as being thixotropic, easily spreadable, Non staining, emollient, bio-friendly, clear, transparent & elegant appearance, & these Microemulgel based formulations enhances the skin deposition of API , thereby ultimately enhancing its therapeutic activity. Keywords: Microemulgel, Topical drug delivery, hydrophobic drugs.

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