ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

VITAMIN D DEFICIENCY: ITS ROLE AND IMPACT ON CARDIOVASCULAR DISEASE.

D.M. Ravi Chand

Vitamin D deficiency seems to be the front runner to cause various cardio-vascular diseases, a number of studies have shown that vitamin D insufficiency is prevalent among many populations among all age groups; this growing menace is of epidemic proportions across all ethnicities. Besides vitamin D established role in calcium homeostasis, its deficiency is emerging as a new risk factor for coronary artery disease. In India the socio-religious and cultural practices do not facilitate adequate sun exposure, thereby negating potential benefits of plentiful sunshine. Vitamin D deficiency is highly prevalent in urban and rural areas, and across all socioeconomic and geographic strata. Vitamin D deficiency seems to predispose to recurrent adverse cardiovascular events, as it is associated with post-infarction complications and cardiac remodeling in patients with acute myocardial infraction. Coronary artery disease due to vitamin D deficiency have been constantly proven, many intervention trials are going on to show difference in terms of risk reduction with supplementation of vitamin D. Vitamin D deficiency not only increases risk for a myocardial infarction by as much as 50% but also was associated with more than one 100 % increased risk of mortality from the heart attack. Further research in this direction is warranted and it is likely to open up new avenues for reducing the risk of cardiovascular disease. Key Words: Vitamin D, myocardial infarction, coronary artery disease, cardiovascular disease.

FULL TEXT